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           Drosophila Lab           

Amit Singh, PhD.   
Associate Professor, 
Director Graduate Program, Department of Biology
Tissue Regeneration and Engineering at Dayton (TREND),    
University of Dayton, Dayton, Ohio, 45469 USA
Tel: 937-229-2894; Fax: 937-229-2021     
Email: asingh1@udayton.edu; amitsingh60@gmail.com
Curriculum Vitae
 

PEER-REVIEWED PUBLICATIONS (IN CHRONOLOGICAL ORDER)

 

  1. Kwon HJ, Waghmare I, Verghese S, Singh A, Singh A, Kango-Singh M. (2014). Drosophila C-terminal Src Kinase regulates growth via the Hippo signaling pathway. Developmental Biology.Oct 22. pii: S0012-1606(14)00526-0. doi: 10.1016/j.ydbio.2014.10.010.  PMID: 25446534 PDF

  2. Kiritooshi, N., Yorimitsu, T., Shirai, T., Puli, O.R., Singh, A., Nakagoshi, N. (2014). A vertex specific dorsal selector dve represses ventral appendage identity in Drosophila head. Mechanism of Development. Jun 24. pii: S0925-4773(14)00031-8. PMID: 24793093 PDF

  3. Moran, M.T., Tare, M., Kango-Singh, M. *, Singh A. (2013) Homeotic gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration. PLoS ONENov 25;8(11):e80829. doi: 10.1371 PMID 24282556 PDF

  4. Steffensemeir, A., Tare, M., Puli, O. R., Modi, R.M., Nainaparampil, J., Kango-Singh*, M., Singh A. * (2013).  Novel neuroprotective function of apical-basal polarity gene crumbs in amyloid beta 42 (Aβ42) mediated neurodegeneration. PLoS ONE Nov 18; 8(11):e78717. doi: 10.1371/journal.pone.0078717 PMID24260128 PDF

  5. Meghana Tare,  Oorvashi Roy Puli, Michael T. Moran, Madhuri Kango-Singh, Singh, A. (2013). Domain specific genetic mosaic system in the Drosophila eye. Genesis 51:68-74. PMID:23109378 PDF

  6. Singh, A., Irvive, K.D. (2012). Drosophila as a model for understanding development and disease (Editorial). Dev Dyn. 2012 Jan;241(1):1-2. doi: 10.1002/dvdy.23712. PDF

  7. Singh, A., Tare, M., Puli- Roy, O., Kango-Singh, M. (2012). A glimpse into Dorso-ventral patterning of the Drosophila eye. (Review). 241(1):69-84. doi: 10.1002/dvdy.22764 PDF

  8. Singh, A., Tare, M., Kango-Singh, M., Son, W.-S., Cho, K.-O. Choi, K.-W. (2011). Opposing interactions between homothorax and Lobe define the ventral eye margin of Drosophila eye. Developmental Biology 359 (2011) 199208. PDF

  9. Tare, M*., Modi, R.M*., Nainaparampil, J.J*., Puli, O.R., Bedi, S., Fernandez-Funez, P., Kango-Singh M., and Singh, A. (2011). Activation of JNK signaling mediates Amyloid-β-dependent cell death. PLoS One (in press) 6(9):e24361. doi:10.1371/journal.pone.0024361. [* Equal Contribution] PDF

  10. Oros, S.M., Tare, M., Kango-Singh, M. and Singh, A.* (2010). Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye. Developmental Biology Dev Biol. 2010 Oct 15;346(2):258-71. Epub 2010 Aug 5. PMID: 20691679  [* Corresponding Author] PDF

  11. Singh, A.*, Kango-Singh, M., and Gopinathan, K.P. (2009).  Patterning defects in silkworm embryos analysed through cuticle preparations. Sericologia 49 (1):113-117.     [* Corresponding Author] PDF

  12. Lim, J. Lee, O.K. Hsu, Y.-C, Singh, A. and Choi, K.-W. (2007b) Drosophila TRAP230/240 are essential coactivators for Atonal in retinal neurogenesis. Developmental Biology  308(2): 322-330  PMID: 17585897  PDF

  13. Singh, A.*, Kango-Singh, M., Parthasarathy, R. and Gopinathan, K.P.  (2007a). Larval legs of mulberry silkworm Bombyx mori are prototypes for the adult legs. Genesis 45 (4): 169-176 PMID: 17417803  [* Corresponding Author] PDF

  14. Singh, A.*, Xiao, S. and Choi, K.-W.* (2006a). Lobe and Serrate, are required for cell survival during early eye development in Drosophila. Development 133, 4771-4781. PMID: 17090721  [* Co-Corresponding Author] PDF

  15. Singh, A., Chan, J., Chern, J.J. and Choi, K.-W. (2005a). Genetic interaction of Lobe with its modifiers in dorsoventral patterning and growth of the Drosophila eye. Genetics. 171(1):169-83. Epub 2005 Jun 23. PMID: 15976174  PDF

  16. Singh, A., Kango-Singh, M., Choi, K.-W. and Sun, Y.H. (2004). Dorso-ventral asymmetric functions of teashirt in Drosophila eye development depend on spatial cues provided by early DV patterning genes. Mechanisms of Development 121: 365-370. PMID: 15110046  PDF

  17. Singh, A., Choi, K.-W. (2003). Initial state of Drosophila eye before dorso-ventral specification is equivalent to ventral. Development 130: 6351-6360. PMID: 14623824  PDF

  18. Kango-Singh, M., Singh, A. and Sun, Y.H.  (2003). Eyeless collaborates with Hedgehog and Decapentaplegic signaling in Drosophila eye induction. Developmental Biology 256 (1):49-60.  PMID: 12654291  PDF

  19. Singh, A., Kango-Singh, M. and Sun, Y.H. (2002). Eye suppression, a novel function of teashirt, requires Wingless signaling. Development 129(18): 4271-80. PMID: 12183379  PDF

  20. Kango-Singh, M.*, Singh, A.* and Gopinathan, K.P. (2001). The wings of Bombyx mori develop from larval discs exhibiting an early differentiated state: a preliminary report.  Journal of Bioscience 26(2), 167-177. PMID: 11426053[Equal first author] PDF    

  21. Singh, A. and Gopinathan, K.P. (1997). Study of gene expression in whole mount silkworm embryos using heterologous Drosophila antibodies. Current Science 72 (2): 214-219. (http://www.ias.ac.in/j_archive/currsci/72/3/214-218/viewpage.html)  PDF

  22. Bhojwani, J., Singh, A., Misquitta, L., Mishra, A. and Sinha, P. (1995). Search for Drosophila genes based on patterned expression of mini-white reporter gene in adult eyes. Roux's Archives of Developmental Biology, 205(3-4): 114-121. http://www.springerlink.com/content/k4267w753752444m/)  PDF

  23. Singh A., Kango, M. and Sinha, P. (1994). An improved method for chemical devitellinization of X-gal stained Drosophila embryos. IJEB 33, 150-152. PMID: 7538973  PDF

     

    B. REVIEWS


  24. Singh, A., Tsonis, P.A. (2010).  Focus on Molecules: Six3 - Master or Apprentice? Experimental Eye Research 90  (2010):535-536. PMID: 20117106  PDF

  25. Kango-Singh, M. and Singh, A.* (2009). Regulation of Organ Size: Insights from the Drosophila Hippo signaling pathway. Dev. Dynamics 238(7):1627-37. PMID: 19517570  [* Co-Corresponding Author] PDF

  26. Singh, A. and Gopinathan, K.P. (1998). Confocal microscopy, a powerful tool for biological research. Current Science 74(10):841- 851. (http://www.ias.ac.in/j_archive/currsci/74/10/841-851/viewpage.html)  PDF

  27. Singh, A. (1995). Enhancer Trap Technique: A Novel Tool for Identification and Developmental Characterization of Genes of Drosophila. Current Science 68: 517-525.  (http://www.ias.ac.in/j_archive/currsci/68/5/517-525/viewpage.html)  PDF


    C. BOOK

  28. Singh, A. and Kango-Singh, M. (2013). Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila eye. Amit Singh (Editor) and Madhuri Kango-Singh (Editor), Springer, Publication Date: September 30, 2013 | ISBN-10: 1461482313 | ISBN-13: 978-1461482314 | Edition: 2013


    D. BOOK CHAPTERS

  29. Tare, M., Roy, O.R., Singh, A. (2013). Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila eye. Amit Singh (Editor) and Madhuri Kango-Singh (Editor), Springer, Publication Date: September 30, 2013 | ISBN-10: 1461482313 | ISBN-13: 978-1461482314 | Edition: 2013

  30. Singh, A., Lim, J., and Choi K.-W (2005b). Dorso-ventral boundary is required for organizing growth and planar polarity in the Drosophila eye. In Planar Cell Polarization during Development: Advances in Developmental Biology and Biochemistry (ed. M. Mlodzik) pp. 59-91, Elsevier Science & Technology Books.  PDF

  31. Gopinathan, K.P., Joy, O., and Singh, A. (1998). Developmental aspects of Mulberry and Nonmulberry Silkworm Species: A comparative study. In " Genome Analysis in Eukaryotes: Developmental and evolutionary aspects " (eds. R. M. Chatterjee and L. Sanchez) pp. 65-97, Springer-Verlag New York, Incorporated.  PDF


    E. TEACHING REPORTS


  32. Puli, O.R. and Singh, A. (2011). Protein trap lines in Drosophila to demonstrate spatio-temporal localization of proteins in an undergraduate lab. Dros. Inf. Serv. (94):190-196. PDF

  33. Usman, M., Singh, A. (2011). A New Undergraduate Curriculum in Mathematical Biology at the University of Dayton. Journal of STEM Education. 12(5 & 6 ): 9-17 July - Sept. 2011.  [* Corresponding Author] PDF

  34. Tare, M. and Singh, A.* (2009). A cell Biology laboratory exercise to study sub-cellular organelles in Drosophila. Dros. Inf. Serv. (91): 160-164.  [* Corresponding Author] PDF

  35. Tare, M., Puli G. Roy O., Oros M.S. and Singh, A.* (2009). Drosophila adult eye model to teach Scanning Electron Microscopy in an undergraduate cell biology laboratory. Dros. Inf. Serv. (92): 174-180.  [* Corresponding Author] PDF


    F. INVITED COMMENTARY & OTHERS


  36. Singh, A.  (2012). Neurodegeneration a means to an end. Journal of Cell Science and Therapy (Editorial). J. Cell Sci. Therapy 3:e107. Doi:10.4172/2157-7013.1000e107.  http://www.omicsonline.org/2157-7013/2157-7013-3-e107.php?aid=6170.

  37. Call, G.B., Puli,O.R, James, A.M., Pope, C. R., Kango-Singh, M., Singh, A.* (2011). Annual Drosophila Research Conference, 2012 Developmental Dynamics. May 16. doi: 10.1002/dvdy.23806 [* Corresponding Author] PDF

  38. Call, G.B., Verghese,S., Puli,O.R, Hemmerle,D.M., Kango-Singh, M., Singh, A.* (2011). Annual Drosophila Research Conference, 2011 Developmental Dynamics. 240:2042-2050.In Press. PMID: 21761487  [* Corresponding Author] PDF

  39. Call, G.B., Roy,Puli.O, Verghese,S., SiSingh, A.* (2010). Annual Drosophila Research Conference,D.C, 2010 Dev. Dynamics. 239(11):3124-9.  PMID: 20865791  [* Corresponding Author] PDF

  40.  Kango-Singh, M., Call, G. B., and Singh, A.*, (2008).  Annual Drosophila meeting at San Diego 2008. Dev. Dynamics 237(11):3444-52. PMID: 18924240 [* Corresponding Author] PDF

  41. Singh, A.*, Kango-Singh, M (2006a).  Annual Drosophila meeting at Houston 2006. Dev. Dynamics. (Published Online: 26 Jul 2006) PMID: 16871634  [* Corresponding Author] PDF

  42. Singh, A.* (2006b). Fly eye development in fly meeting at Houston. Int. J. Dev. Biol. 50: 659-663. PMID: 17051475  [* Corresponding Author] PDF

  43. Singh, A.*, Kango, M. (1995). An improved devitellinization technique with a high yield of X-gal stained embryos.    Dros. Inf. Serv.  76:215.